Subtracting 2 lists in Python

Right now I have vector3 values represented as lists. is there a way to subtract 2 of these like vector3 values, like

[2,2,2] - [1,1,1] = [1,1,1]

Should I use tuples?

If none of them defines these operands on these types, can I define it instead?

If not, should I create a new vector3 class?